Description

2-Ethynyl-4,5-Difluoro-Phenylamine is a specialized aromatic amine derivative featuring both ethynyl and fluorine substituents. This compound is a high-value intermediate prized for its unique reactivity profile, enabling the synthesis of complex molecular architectures. It is primarily sought by research and development teams in the pharmaceutical and advanced materials sectors for applications in medicinal chemistry and organic electronics.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for targeted therapies.
• Agrochemical Research: Used in the development of new generation herbicides and pesticides with enhanced efficacy.
• Material Science: Serves as a precursor for functionalized polymers and advanced organic electronic materials.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Fluorescent Probe Development: Utilized in the creation of sensing molecules and biomarkers for diagnostic applications.
• Academic & Industrial R&D: A valuable reagent for exploratory chemistry in both university and corporate research laboratories.

Basic Information

Product Name	2-Ethynyl-4,5-Difluoro-Phenylamine
CAS No.	143101-25-1
Molecular Formula	C8H5F2N
Molecular Weight	153.13 g/mol
Synonyms	4,5-Difluoro-2-ethynylaniline; 2-Amino-4,5-difluorophenylacetylene; 2-Ethynyl-4,5-difluoroaniline; 4,5-Difluoro-2-ethynylbenzenamine; 2-Ethynyl-4,5-difluorobenzenamine; (4,5-Difluoro-2-aminophenyl)acetylene
EINECS	Contact for details

Quality Control

Our production of 2-Ethynyl-4,5-Difluoro-Phenylamine adheres to stringent internal quality protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to light.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.