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D-Arg-D-Pro-Lys-Pro-Gln-Gln-D-Trp-Phe-D-Trp-Leu-Leu-Nh2 Acetate Salt CAS NO 143077-65-0


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CAS No.:143077-65-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

D-Arg-D-Pro-Lys-Pro-Gln-Gln-D-Trp-Phe-D-Trp-Leu-Leu-Nh2 Acetate Salt is a synthetic peptide acetate salt, a derivative of the potent neuropeptide bombesin. This compound is of significant interest for advanced biochemical and pharmacological research due to its receptor-binding properties. It is primarily utilized by research institutions and pharmaceutical developers focusing on oncology, neurobiology, and diagnostic imaging.

Application

  • Biomedical Research: As a high-purity reference standard in studies of bombesin receptor subtypes (BB1, BB2, BB3).
  • Drug Discovery: A key intermediate or tool compound for developing novel targeted cancer therapies and diagnostic agents.
  • In Vitro Diagnostics: Used in the development of immunoassays and receptor-binding assays for research purposes.
  • Academic Research: Investigation of neuropeptide signaling pathways, tumor biology, and cellular proliferation mechanisms.
  • Radiopharmaceutical Development: Serves as a precursor for radiolabeled peptides used in Positron Emission Tomography (PET) imaging.

Basic Information

Product Name D-Arg-D-Pro-Lys-Pro-Gln-Gln-D-Trp-Phe-D-Trp-Leu-Leu-Nh2 Acetate Salt
CAS No. 143077-65-0
Molecular Formula C86H122N24O16 • xC2H4O2
Molecular Weight ~1790.1 g/mol (free base)
Synonyms Bombesin (6-14), D-Arg1, D-Pro2, D-Trp7,9, Leu11-, ψ13-14 Peptide Amide; [D-Arg1, D-Pro2, D-Trp7,9, Leu11]Bombesin(6-14); Bombesin Receptor Antagonist Peptide; RC-3095; Tyr4-Bombesin Analog; BIM 26226; BIM-26226
EINECS Contact for details

Quality Control

Our peptide products are manufactured under strict quality systems. Each batch of D-Arg-D-Pro-Lys-Pro-Gln-Gln-D-Trp-Phe-D-Trp-Leu-Leu-Nh2 Acetate Salt undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing HPLC purity, mass spectrometry (MS) data, and amino acid analysis are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item Specification
Appearance White to off-white powder
Identification (HPLC) Conforms to reference standard
Identification (MS) Conforms to theoretical mass
Purity (HPLC) ≥ 95.0%
Single Impurity (HPLC) ≤ 2.0%
Water Content (KF) ≤ 8.0%
Acetate Content (HPLC/IC) 1.0 - 10.0%
Peptide Content ≥ 70.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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