Description

Serine, n-(Methoxycarbonyl)-, Methyl Ester is a protected serine derivative, a crucial building block in organic synthesis and peptide chemistry. This compound is valued for its role in introducing the serine amino acid moiety into complex molecules while preventing unwanted side reactions during synthesis. It is primarily needed by research institutions and manufacturers in the pharmaceutical, biotechnology, and agrochemical sectors for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediates: A key synthon in the production of peptide-based drugs, protease inhibitors, and other bioactive molecules.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) as a protected serine residue to ensure regioselectivity.
• Bioconjugation: Serves as a linker or spacer molecule in the development of antibody-drug conjugates (ADCs) and other bioconjugates.
• Chemical Research: Employed in academic and industrial R&D for exploring new synthetic methodologies and constructing complex organic architectures.
• Agrochemical Development: Utilized in the synthesis of novel herbicides, fungicides, or plant growth regulators that incorporate amino acid motifs.
• Protecting Group Strategy: The methoxycarbonyl (Moc) and methyl ester groups offer orthogonal protection, useful in multi-step synthetic sequences.

Basic Information

Product Name	Serine, n-(Methoxycarbonyl)-, Methyl Ester
CAS No.	143076-21-5
Molecular Formula	C7H13NO5
Molecular Weight	191.18 g/mol
Synonyms	N-Methoxycarbonylserine Methyl Ester; Methyl N-Methoxycarbonylserinate; Serine, N-(methoxycarbonyl)-, methyl ester; L-Serine, N-(methoxycarbonyl)-, methyl ester (if applicable); Moc-Ser-OMe; N-Carbomethoxy-L-serine methyl ester; Methyl (2S)-2-[(methoxycarbonyl)amino]-3-hydroxypropanoate; Methyl 2-[(methoxycarbonyl)amino]-3-hydroxypropanoate
EINECS	Contact for details

Quality Control

Our Serine, n-(Methoxycarbonyl)-, Methyl Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm stereochemical integrity, and identity confirmation via IR and NMR spectroscopy. We provide Certificates of Analysis (COA) with each shipment, detailing all critical parameters to ensure compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee (if applicable)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.