Description

Fmoc-Ser(Tbu)-Pro-OH ≥ 95% (HPLC) is a protected dipeptide building block widely used in solid-phase peptide synthesis (SPPS). This high-purity reagent is critical for the efficient and controlled assembly of complex peptide sequences, particularly in pharmaceutical research and development. It is essential for scientists and manufacturers in the biotechnology, pharmaceutical, and academic research sectors who require reliable, high-quality intermediates for peptide-based drug discovery and development.

Application

• Solid-Phase Peptide Synthesis (SPPS): A fundamental building block for the stepwise construction of custom peptide sequences using Fmoc-chemistry protocols.
• Pharmaceutical R&D: Used in the research and development of therapeutic peptides, including hormone analogs, antimicrobial peptides, and targeted drug delivery systems.
• Combinatorial Chemistry: Employed in libraries for high-throughput screening to identify novel bioactive peptide leads.
• Bioconjugation: Serves as a precursor for creating peptide-protein or peptide-small molecule conjugates for diagnostic and therapeutic applications.
• Academic Research: A standard reagent in university and institutional labs for studying protein structure-function relationships, enzyme substrates, and signal transduction pathways.
• Production of Peptide Fragments: Used in the synthesis of specific peptide segments for fragment condensation or native chemical ligation strategies.

Basic Information

Item	Details
Product Name	Fmoc-Ser(Tbu)-Pro-OH ≥ 95% (HPLC)
CAS No.	143038-46-4
Molecular Formula	C27H32N2O6
Molecular Weight	480.55 g/mol
Synonyms	Fmoc-Ser(tBu)-Pro-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-(tert-butyl)-L-seryl-L-proline; Fmoc-O-tert-butyl-L-seryl-L-proline; Fmoc-Ser(O-tBu)-Pro-OH; Fmoc-L-Ser(tBu)-L-Pro-OH; Nα-Fmoc-O-tert-butyl-L-seryl-L-proline; (2S)-2-[[(2S)-2-[(9H-fluoren-9-ylmethoxy)carbonylamino]-3-[(2-methylpropan-2-yl)oxy]propanoyl]amino]pyrrolidine-1-carboxylic acid
EINECS	Contact for details

Quality Control

Our Fmoc-Ser(Tbu)-Pro-OH is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity verification, to ensure it meets the high standards required for sensitive peptide synthesis applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥ 95.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.