Description

3,4-Dimethy-L-Phenylalanine is a non-natural, chiral amino acid derivative that serves as a critical building block in advanced organic synthesis. Its value lies in providing a sterically defined, dimethyl-substituted aromatic side chain, enabling the fine-tuning of peptide and small molecule properties. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly for developing novel active pharmaceutical ingredients (APIs), peptide therapeutics, and chiral catalysts.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel drug candidates, especially in central nervous system (CNS) and metabolic disorder therapies.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate a hydrophobic, sterically hindered aromatic moiety, influencing peptide folding, stability, and receptor binding.
• Asymmetric Catalysis: Employed as a precursor or ligand in chiral catalysts for stereoselective synthesis, crucial for producing enantiomerically pure compounds.
• Biochemical Research: Utilized as a substrate analog or inhibitor in enzymatic studies to investigate substrate specificity and enzyme mechanisms.
• Agrochemical Development: Serves as an intermediate in the synthesis of advanced, chiral agrochemicals with improved efficacy and environmental profiles.
• Material Science: A potential monomer for constructing specialty polymers and functional materials with tailored aromatic characteristics.

Basic Information

Product Name	3,4-Dimethy-L-Phenylalanine
CAS No.	142995-28-6
Molecular Formula	C11H15NO2
Molecular Weight	193.24 g/mol
Synonyms	L-3,4-Dimethylphenylalanine; (S)-2-Amino-3-(3,4-dimethylphenyl)propanoic acid; 3,4-Dimethyl-L-α-aminohydrocinnamic acid; 3,4-Dimethyl-DL-phenylalanine (related to racemic mixture); H-3,4-Dimethyl-Phe-OH; 3,4-DMPA; 3,4-Dimethylphenylalanine; 3,4-Xylyl-L-alanine
EINECS	Contact for details

Quality Control

Our 3,4-Dimethy-L-Phenylalanine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. A Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% (L-isomer)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.