Description

(Tyr0)-C-Type Natriuretic Peptide (32-53) (Human, Porcine, Rat) is a synthetic peptide fragment corresponding to a specific region of the C-type natriuretic peptide (CNP) molecule. This high-purity research-grade compound is essential for advancing cardiovascular and renal research, serving as a critical tool for studying CNP receptor binding, signal transduction pathways, and physiological functions. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on peptide-based therapeutics and diagnostic assay development.

Application

• Biomedical Research: Used as a reference standard and active agent in studies investigating the vasodilatory, diuretic, and natriuretic properties of CNP.
• Receptor Binding Assays: Critical for competitive binding studies to characterize and quantify CNP receptors (NPR-B) in various tissue preparations.
• Signal Transduction Studies: Employed to elucidate downstream cellular signaling cascades activated by CNP, including cGMP pathways.
• Antibody Production & Immunoassays: Serves as an immunogen for generating specific antibodies or as a calibrator in ELISA and RIA development for CNP detection.
• Pharmaceutical Screening: Used in high-throughput screening (HTS) platforms to identify and validate novel modulators of the natriuretic peptide system.
• Comparative Physiology: Facilitates cross-species studies (Human, Porcine, Rat) to understand evolutionary conservation and functional differences of CNP.

Basic Information

Product Name	(Tyr0)-C-Type Natriuretic Peptide (32-53) (Human, Porcine, Rat)
CAS No.	142878-79-3
Molecular Formula	C115H184N36O38S2
Molecular Weight	2630.1 g/mol
Synonyms	Tyr0-CNP (32-53); CNP-22 (Tyr0); C-Type Natriuretic Peptide (32-53), Tyr0-substituted; H-Tyr-Gly-Leu-Ser-Lys-Gly-Cys-Phe-Gly-Leu-Lys-Leu-Asp-Arg-Ile-Gly-Ser-Met-Ser-Gly-Leu-Gly-Cys-NH2 (Disulfide bridge: Cys7-Cys23); [Tyr0]CNP-22; Human Porcine Rat CNP (32-53) fragment; CNP-22 analog
EINECS	Contact for details

Quality Control

Every batch of (Tyr0)-C-Type Natriuretic Peptide (32-53) is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality commitment aligns with standards expected for research biochemicals. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing results for purity (HPLC), molecular weight confirmation (MS), and peptide content.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Molecular weight confirmed by Mass Spectrometry
Purity (HPLC)	≥ 95% (Area Percent)
Peptide Content	≥ 80% (by weight)
Amino Acid Analysis	Complies with theoretical composition

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.