Description

1H-Azepine-1-Aceticacid,3-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]Hexahydro-2-Oxo-,(3S)-(9Ci) CAS NO 142855-79-6 is a sophisticated, optically pure building block used in advanced organic synthesis. This compound is critical for the development of novel peptide-based therapeutics and complex molecular architectures due to its specific stereochemistry and protected functional groups. It is primarily utilized by research institutions and pharmaceutical companies engaged in peptidomimetic drug discovery, process development, and the synthesis of high-value active pharmaceutical ingredients (APIs).

Application

• Solid-Phase Peptide Synthesis (SPPS): Serves as a key Fmoc-protected amino acid derivative for the controlled assembly of complex peptides.
• Pharmaceutical Intermediate: Used in the research and development of novel therapeutic agents, particularly in oncology and metabolic disease research.
• Peptidomimetic Scaffold Development: Acts as a core structural element for designing molecules that mimic peptides with improved stability and bioavailability.
• Bioconjugation Chemistry: Employed in the synthesis of peptide-drug conjugates (PDCs) and other targeted delivery systems.
• Academic and Industrial R&D: A valuable reagent for methodological studies in organic chemistry and medicinal chemistry programs.
• Custom Synthesis: Used as a starting material for the bespoke production of specialized fine chemicals and reference standards.

Basic Information

Product Name	1H-Azepine-1-Aceticacid,3-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]Hexahydro-2-Oxo-,(3S)-(9Ci)
CAS No.	142855-79-6
Molecular Formula	C23H24N2O5
Molecular Weight	408.45 g/mol
Synonyms	Fmoc-(S)-Aze-OH; Fmoc-L-Azetidine-2-carboxylic acid (common trade/abbreviation); (3S)-3-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]hexahydro-2-oxo-1H-azepine-1-acetic acid; Fmoc-Aze-OH; 1H-Azepine-1-acetic acid, 3-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]hexahydro-2-oxo-, (3S)-; N-α-Fmoc-L-azetidine-2-carboxylic acid; Fmoc-L-2-carboxyazetidine; Fmoc-azetidine-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of this high-purity building block adheres to stringent quality management systems. Every batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure identity, purity, and chiral integrity. A comprehensive Certificate of Analysis (COA) detailing assay, chiral purity, and impurity profiles is provided with each shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label or COA. This product is hygroscopic (moisture-sensitive); ensure the container is sealed under inert atmosphere after each use to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% (S-isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.