Description

Fmoc-Val-Gly-Oh CAS NO 142810-19-3 is a protected dipeptide building block extensively used in solid-phase peptide synthesis (SPPS). This compound is critical for researchers and manufacturers requiring high-purity intermediates to construct complex peptide sequences with precise control. It is primarily utilized by the pharmaceutical, biotechnology, and life sciences industries for applications ranging from drug discovery to the development of therapeutic peptides and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A fundamental Fmoc-protected dipeptide for the sequential assembly of custom peptide chains.
• Pharmaceutical Intermediates: Serves as a key raw material in the research and production of active pharmaceutical ingredients (APIs) for peptide-based drugs.
• Bioconjugation & Probe Development: Used to introduce specific Val-Gly sequences into fluorescent probes, affinity tags, or protein conjugates for biochemical studies.
• Combinatorial Chemistry Libraries: Employed in the generation of diverse peptide libraries for high-throughput screening in drug discovery campaigns.
• Academic & Industrial Research: A standard reagent for studying peptide structure-activity relationships (SAR) and developing novel biomaterials.
• Custom Peptide Service Providers: An essential inventory item for CROs and CDMOs offering bespoke peptide synthesis services.

Basic Information

Product Name	Fmoc-Val-Gly-Oh
CAS No.	142810-19-3
Molecular Formula	C22H24N2O5
Molecular Weight	396.44 g/mol
Synonyms	Fmoc-Val-Gly-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-valylglycine; Fmoc-L-valylglycine; Fmoc-Val-Gly; (9-Fluorenylmethyloxycarbonyl)-L-valyl-glycine; N-Fmoc-L-valylglycine; Fmoc-VG-OH; Fmoc-Val-Glycine
EINECS	Contact for details

Quality Control

Our Fmoc-Val-Gly-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the stringent requirements for peptide synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and compliance with your research or cGMP-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥98.0%
Specific Rotation	-15.0° to -19.0° (c=1, DMF)
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.