Description

2-((2S,3S)-2-(((9H-Fluoren-9-Yl)Methoxy)Carbonylamino)-3-Methylpentanamido)Acetic Acid is a sophisticated, optically pure Fmoc-protected amino acid derivative. This compound is a critical building block in the synthesis of complex peptides and peptidomimetics, offering precise stereochemical control. It is primarily utilized by research institutions and pharmaceutical companies engaged in advanced drug discovery and development programs.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key Fmoc-protected amino acid for the sequential assembly of custom peptides.
• Pharmaceutical Intermediates: Serves as a crucial intermediate in the synthesis of therapeutic peptides targeting various diseases.
• Bioconjugation: Used to introduce specific amino acid sequences or functional handles into biomolecules like proteins or antibodies.
• Chemical Biology Research: A valuable tool for studying protein-protein interactions and enzyme mechanisms through the creation of peptide probes.
• Peptidomimetic Development: Enables the creation of non-natural peptide analogs with enhanced stability and biological activity.
• High-Purity Reference Standard: Employed as a certified reference material for analytical method development and quality control in peptide manufacturing.

Basic Information

Product Name	2-((2S,3S)-2-(((9H-Fluoren-9-Yl)Methoxy)Carbonylamino)-3-Methylpentanamido)Acetic Acid
CAS No.	142810-18-2
Molecular Formula	C24H26N2O6
Molecular Weight	438.48 g/mol
Synonyms	Fmoc-L-Ile-Asp-OH; Fmoc-Ile-Asp-OH; Fmoc-Ile-Aspartic Acid; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-isoleucyl-L-aspartic acid; (2S,3S)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-3-methylpentanoyl]amino]acetic acid; Fmoc-Ile-Asp(OtBu)-OH (precursor form); Fmoc-L-Isoleucyl-L-aspartic acid
EINECS	Contact for details

Quality Control

Our production of this high-value building block adheres to stringent quality protocols. Every batch is subjected to comprehensive analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity, ensuring it meets the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.