Description

(Lys7)-Dermorphin CAS NO 142689-18-7 is a synthetic peptide analog of the potent opioid heptapeptide Dermorphin, modified with a lysine substitution at position 7. This modification is designed to enhance its stability, bioavailability, and research utility in studying opioid receptor interactions. It is a critical tool for advanced biochemical and pharmacological research, particularly in neuroscience and pain management studies. This high-purity compound is essential for academic institutions, pharmaceutical R&D laboratories, and biotechnology companies focused on neuropeptide and analgesic drug discovery.

Application

• Neuroscience Research: Used as a selective ligand for studying mu-opioid receptor (MOR) binding, activation, and signaling pathways in vitro and in vivo.
• Analgesic Mechanism Studies: Serves as a reference standard in research investigating the structure-activity relationships (SAR) of opioid peptides and the development of novel pain therapeutics.
• Biochemical Assay Development: Employed in the development and validation of receptor binding assays, cell-based functional assays, and other pharmacological test systems.
• Peptide Chemistry & Drug Discovery: Acts as a key intermediate or reference compound for designing and synthesizing new peptide-based analogs with improved metabolic stability or receptor selectivity.
• Academic & Pharmaceutical R&D: Provides a reliable, high-purity research chemical for universities, contract research organizations (CROs), and drug discovery teams.

Basic Information

Product Name	(Lys7)-Dermorphin
CAS No.	142689-18-7
Molecular Formula	C44H62N12O10
Molecular Weight	918.04 g/mol
Synonyms	H-Tyr-D-Ala-Phe-Gly-Tyr-Pro-Lys-NH2; [Lys7]-Dermorphin; Dermorphin, 7-L-lysine-; Dermorphin (Lys7)-; L-Lysine-Dermorphin; Opioid peptide analog (Lys7); Tyr-D-Ala-Phe-Gly-Tyr-Pro-Lys-NH2; H-Tyr-D-Ala-Phe-Gly-Tyr-Hyp-Lys-NH2 (Hydroxyproline variant)
EINECS	Contact for details

Quality Control

Our (Lys7)-Dermorphin is manufactured under strict quality control protocols to ensure the highest standards of purity and consistency for research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to ISO 9001 quality management principles, and our analytical methods are validated to meet the rigorous demands of pharmaceutical and life science research. Certificates of Analysis are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant or under an inert atmosphere. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Assay (HPLC)	≥ 98.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Single Impurity (HPLC)	≤ 1.0%
Peptide Content	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.