Description

Glycylmelittin is a synthetic peptide analog of the potent bee venom component, melittin, modified with an N-terminal glycine residue. This modification is designed to modulate its biological activity and physicochemical properties, making it a valuable tool for advanced biochemical and pharmacological research. It is primarily utilized by researchers and developers in the fields of peptide chemistry, biophysics, and drug discovery. The compound is supplied under the identifier CAS No. 142647-80-1.

Application

Glycylmelittin is employed in a variety of specialized research and development applications, including:

• Biophysical Studies: Investigation of peptide-lipid membrane interactions, pore-formation mechanisms, and structural dynamics.
• Drug Discovery Platforms: Serving as a lead compound or a model system for developing novel antimicrobial or anticancer agents.
• Cell Biology Research: Studying membrane permeabilization, cell lysis, and intracellular delivery mechanisms.
• Toxin-Antitoxin Research: Used as a reference standard or active component in studies of venom biology and neutralization strategies.
• Peptide Engineering: As a template for structure-activity relationship (SAR) studies to understand the impact of specific amino acid modifications.

Basic Information

Product Name	Glycylmelittin
CAS No.	142647-80-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Gly-Melittin; N-Glycylmelittin; Melittin, N-glycyl-; Glycine-melittin conjugate; H-Gly-Melittin-OH; G-Melittin; Peptide G-Mel
EINECS	Contact for details

Quality Control

Our Glycylmelittin is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot undergoes comprehensive analytical characterization, including purity assessment by HPLC and mass spectrometry. A Certificate of Analysis (COA) detailing identity, purity, and other relevant parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, DMSO, acetic acid solutions

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.