Description

Glutamyl-Lysyl-Valyl-Isoleucyl-Serine is a synthetic pentapeptide sequence of significant interest in biochemical research and pharmaceutical development. This compound is valued for its role as a model substrate in enzymatic studies and as a potential building block for more complex bioactive peptides. It is primarily utilized by research institutions and pharmaceutical companies engaged in proteomics, enzyme kinetics, and novel therapeutic discovery. The precise structure allows for targeted investigation into peptide-protein interactions and metabolic pathways.

Application

• Biochemical Research: Serves as a standard or substrate in enzymatic assays and proteomics studies to understand cleavage specificity and kinetics.
• Pharmaceutical R&D: Used as an intermediate or reference compound in the discovery and development of peptide-based therapeutics and diagnostic agents.
• Protease/Enzyme Characterization: Acts as a specific peptide sequence to characterize the activity and inhibition of proteases like kallikreins or other serine proteases.
• Cell Culture & Signaling Studies: Employed in research to investigate the effects of specific peptide sequences on cellular signaling pathways and receptor binding.
• Cosmeceutical Research: Investigated for potential applications in advanced skincare formulations targeting specific enzymatic processes in the skin.
• Academic & Institutional Laboratories: A key reagent for graduate and post-doctoral research in biochemistry, molecular biology, and medicinal chemistry.

Basic Information

Product Name	Glutamyl-Lysyl-Valyl-Isoleucyl-Serine
CAS No.	142525-10-8
Molecular Formula	C28H50N8O10
Molecular Weight	658.75 g/mol
Synonyms	Glu-Lys-Val-Ile-Ser; EKVIS; GKVIS; H-Glu-Lys-Val-Ile-Ser-OH; L-Glutamyl-L-lysyl-L-valyl-L-isoleucyl-L-serine; Pentapeptide GKVIS; (S)-2-((S)-6-Amino-2-((S)-2-((S)-2-amino-3-methylpentanamido)-3-methylbutanamido)hexanamido)pentanedioic acid
EINECS	Contact for details

Quality Control

Our Glutamyl-Lysyl-Valyl-Isoleucyl-Serine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, MS for identity confirmation, and chiral analysis to ensure stereochemical integrity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures material suitable for demanding research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider desiccated conditions at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Composition	Conforms to theoretical ratio
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.