Description

N(Alpha)(N,n-Dimethylcarbamoyl)-α-Azalysine 4-Nitrophenyl Ester is a specialized synthetic amino acid derivative and activated ester, widely recognized by its CAS registry number 142182-00-1. This compound serves as a critical building block and reagent in advanced organic synthesis, particularly for the controlled formation of peptide bonds and the introduction of modified lysine residues. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors who require high-purity intermediates for drug discovery, proteomics research, and the development of novel therapeutic peptides.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel peptide-based drugs and active pharmaceutical ingredients (APIs).
• Proteomics Research: Used as a reagent for site-specific protein labeling and modification, enabling advanced biochemical studies.
• Peptide Synthesis: Acts as an activated ester for efficient and selective amide bond formation in solid-phase and solution-phase peptide synthesis.
• Bioconjugation: Facilitates the covalent attachment of peptides or other molecules to carriers, surfaces, or biomolecules for diagnostic and therapeutic applications.
• Chemical Biology Tool: Employed to probe enzyme activity or to create affinity probes for target identification in drug discovery.
• Academic & Industrial R&D: Serves as a high-value research chemical for developing new synthetic methodologies and bioactive compounds.

Basic Information

Product Name	N(Alpha)(N,n-Dimethylcarbamoyl)-α-Azalysine 4-Nitrophenyl Ester
CAS No.	142182-00-1
Molecular Formula	C16H23N5O5
Molecular Weight	365.39 g/mol
Synonyms	N(α)-(N,N-Dimethylcarbamoyl)-α-azalysine 4-nitrophenyl ester; Nα-(N,N-Dimethylcarbamoyl)-α-azalysine p-nitrophenyl ester; (2S)-2-[(Dimethylcarbamoyl)amino]-6-azido-N-(4-nitrophenoxy)hexanamide; Azalysine derivative; Activated azalysine ester; Peptide coupling reagent; Lysine modification reagent
EINECS	Contact for details

Quality Control

Our N(Alpha)(N,n-Dimethylcarbamoyl)-α-Azalysine 4-Nitrophenyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and specific tests for residual solvents and moisture content. We provide comprehensive Certificates of Analysis (COA) to ensure traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Keep container tightly sealed in a desiccator after opening.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.