Description

Pth (1-34) (Porcine) is a synthetic peptide fragment corresponding to the first 34 amino acids of the porcine parathyroid hormone. This biologically active sequence is a critical research tool for studying calcium and phosphate metabolism, bone physiology, and endocrine signaling pathways. It is essential for researchers and developers in the pharmaceutical, biotechnology, and life science sectors focused on metabolic disorders and bone-related therapeutics.

Application

• Biomedical Research: Used as a reference standard and active agent in studies of parathyroid hormone (PTH) receptor binding, signal transduction, and biological activity.
• Drug Discovery & Development: Serves as a key intermediate or pharmacological tool in the development of novel therapeutics for osteoporosis, hypoparathyroidism, and chronic kidney disease-mineral and bone disorder (CKD-MBD).
• In Vitro & In Vivo Assays: Employed in cell-based assays and animal models to investigate the effects of PTH on bone formation, renal calcium reabsorption, and phosphate homeostasis.
• Diagnostic Development: Utilized in the calibration and validation of immunoassays and biosensors designed to measure PTH levels in biological samples.
• Peptide Chemistry & Conjugation: Acts as a substrate for chemical modification, labeling (e.g., with fluorophores or biotin), or conjugation studies to create novel research probes.
• Academic & Institutional Research: Fundamental tool for university and institutional laboratories exploring endocrinology, bone biology, and molecular pharmacology.

Basic Information

Product Name	Pth (1-34) (Porcine)
CAS No.	142007-47-4
Molecular Formula	C181H291N55O51S2
Molecular Weight	~4107.7 g/mol
Synonyms	Parathyroid Hormone (1-34), porcine; PTH (1-34), swine; Teriparatide (porcine sequence); Parathyrin (1-34); PTH 1-34 (porcine); NPS 2143 (sequence variant reference); H2N-SVSEIQLMHNLGKHLNSMERVEWLRKKLQDVHNF-COOH (porcine); Parathyroid hormone fragment 1-34 (porcine).
EINECS	Contact for details

Quality Control

Our Pth (1-34) (Porcine) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with research-grade specifications. Custom synthesis to meet specific purity or packaging requirements is available.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to reach room temperature in a dry environment before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by AAA)
Water Content (KF)	≤ 5.0%
Acetate Content (HPIC)	≤ 10.0%
Biological Activity	Determined by in vitro assay (e.g., cAMP induction)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.