Description

4-Chloro-5-Methyl-2-Piperidinopyrimidine is a high-purity heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceutical agents and agrochemicals, enabling the construction of complex molecular architectures. It is primarily needed by research institutions and industrial R&D departments focused on medicinal chemistry, particularly in the discovery of kinase inhibitors and other biologically active small molecules.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of potential drug candidates, especially for kinase-targeted therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel bioactive compounds.
• Agrochemical Development: Serves as a precursor in the research and synthesis of new pesticides and herbicides.
• Chemical Biology Probes: Utilized in the design and creation of molecular probes for studying biological pathways and target validation.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis projects.
• Academic Research: A valuable reagent for universities and research institutes exploring new heterocyclic chemistry and reaction methodologies.

Basic Information

Product Name	4-Chloro-5-Methyl-2-Piperidinopyrimidine
CAS No.	141924-02-9
Molecular Formula	C10H14ClN3
Molecular Weight	211.69 g/mol
Synonyms	2-(Piperidin-1-yl)-4-chloro-5-methylpyrimidine; 4-Chloro-5-methyl-2-(1-piperidinyl)pyrimidine; 4-Chloro-5-methyl-2-piperidin-1-ylpyrimidine; 2-Piperidino-4-chloro-5-methylpyrimidine; 141924-02-9; 4-Chloro-5-methyl-2-(piperidin-1-yl)pyrimidine
EINECS	Contact for details

Quality Control

Our 4-Chloro-5-Methyl-2-Piperidinopyrimidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. The product undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications and test results are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.