Description

2,6-Difluoro-4-Iodoaniline is a high-purity halogenated aniline derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of fluorine and iodine atoms on the aromatic ring, which enables precise structural modifications and facilitates cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for fluorinated drug candidates targeting central nervous system and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, pesticides, and fungicides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorine-containing aromatic compounds used in electronic display technologies and organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Heck couplings for constructing complex biaryl systems.
• Fluorine Chemistry Research: A valuable reagent for academic and industrial R&D focused on introducing fluorine into complex molecules to modulate their physicochemical properties.
• Dye & Pigment Intermediate: Employed in the synthesis of specialized halogenated dyes and pigments that require specific light-fastness and color properties.

Basic Information

Product Name	2,6-Difluoro-4-Iodoaniline
CAS No.	141743-49-9
Molecular Formula	C6H4F2IN
Molecular Weight	254.99 g/mol
Synonyms	4-Iodo-2,6-difluoroaniline; 2,6-Difluoro-4-iodobenzenamine; Benzenamine, 2,6-difluoro-4-iodo-; 4-Amino-3,5-difluoroiodobenzene; 2,6-Difluoro-4-iodoaniline; 141743-49-9 (CAS); 2,6-DFIA
EINECS	Contact for details

Quality Control

Every batch of 2,6-Difluoro-4-Iodoaniline is produced under a strict quality management system and undergoes comprehensive analytical testing to ensure consistency and purity. We provide a Certificate of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and identity confirmation. Our quality protocols are designed to meet the stringent requirements of cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant secondary packaging.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.