Description

Galanin (2-29) (Rat) is a bioactive peptide fragment derived from the full-length galanin neuropeptide. This compound is a critical research tool for investigating the diverse physiological roles of galanin, particularly in the central and peripheral nervous systems. It is essential for scientists in the fields of neuroscience, endocrinology, and pharmacology studying mechanisms related to pain, cognition, feeding behavior, and hormone release. The product is supplied as a high-purity, lyophilized powder to ensure reliable and reproducible experimental results.

Application

• Neuroscientific Research: Used as a receptor ligand to study galanin receptor (GalR1, GalR2, GalR3) signaling pathways, neuronal excitability, and synaptic transmission.
• Behavioral Pharmacology: Applied in animal models to investigate the effects of galanin on pain perception, anxiety, depression, learning, and memory processes.
• Endocrine Studies: Employed to examine the modulation of hormone secretion, including insulin, glucagon, and growth hormone, by galaninergic systems.
• Biochemical Assay Development: Serves as a standard or reference compound in competitive binding assays (e.g., RIA, ELISA) and activity-based screens.
• Drug Discovery: Acts as a lead structure or tool compound for the design and evaluation of novel galanin receptor agonists or antagonists for therapeutic applications.
• Academic & Institutional Research: Fundamental reagent for university and pharmaceutical R&D laboratories focusing on peptide neurobiology.

Basic Information

Product Name	Galanin (2-29) (Rat)
CAS No.	141696-11-9
Molecular Formula	C145H226N44O41S
Molecular Weight	3169.6 g/mol
Synonyms	Galanin (2-29), rat; Galanin (2-29) amide, rat; Galanin Message-Associated Peptide (GMAP) (2-29); H-Gly-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-His-Ala-Ile-Asp-Asn-His-Arg-Ser-Phe-His-Asp-Lys-Tyr-Gly-Leu-Ala-NH2; Galanin fragment 2-29; rGalanin(2-29); Galanin-related peptide
EINECS	Contact for details

Quality Control

Every batch of Galanin (2-29) (Rat) is manufactured and analyzed under strict quality management protocols. Our products undergo rigorous quality testing to ensure compliance with industry standards for research-grade peptides. Standard quality control includes determination of purity by HPLC, verification of molecular weight by mass spectrometry (MS), and amino acid analysis. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store the lyophilized powder at -20°C or below for long-term stability. For short-term storage, keep at 2-8°C. The product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to prevent moisture absorption. Solutions should be prepared in appropriate buffers (e.g., PBS, 0.1% BSA) and aliquoted for single use to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Molecular weight confirmed by mass spectrometry
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by amino acid analysis)
Solubility	Soluble in water, dilute acetic acid, or appropriate aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.