Description

H-Gly-Pro-Gly-Nh2 Hcl is a high-purity, synthetic tripeptide derivative, specifically the hydrochloride salt of the H-Gly-Pro-Gly-NH₂ sequence. This compound is valued for its role as a key intermediate and building block in advanced pharmaceutical research and peptide synthesis. It is primarily utilized by research institutions, pharmaceutical developers, and fine chemical manufacturers engaged in drug discovery, proteomics, and the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the solid-phase and solution-phase synthesis of more complex therapeutic peptides and peptidomimetics.
• Biochemical Research: Used as a substrate or standard in enzymatic studies, proteomics research, and investigations into peptide structure-activity relationships (SAR).
• Drug Discovery: Employed in high-throughput screening (HTS) libraries and as a precursor for developing potential drug candidates targeting various biological pathways.
• Reference Standard: Functions as a high-purity analytical standard for quality control and method development in HPLC, LC-MS, and other analytical techniques within QC/QA laboratories.

Basic Information

Product Name	H-Gly-Pro-Gly-Nh2 Hcl
CAS No.	141497-12-3
Molecular Formula	C₁₀H₁₇N₅O₄ • HCl
Molecular Weight	307.73 g/mol
Synonyms	Glycyl-L-prolylglycinamide hydrochloride; H-Gly-Pro-Gly-NH₂ • HCl; G-P-G-NH₂ hydrochloride; L-Glycyl-L-prolylglycinamide monohydrochloride; Tripeptide G-P-G-NH₂ HCl; 141497-12-3; Gly-Pro-Gly-NH₂ hydrochloride
EINECS	Contact for details

Quality Control

Our H-Gly-Pro-Gly-Nh2 Hcl is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry guidelines to support our clients' regulatory and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry conditions to maintain stability and purity. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.