Description

Argatroban is a potent, selective, and reversible direct thrombin inhibitor used as an anticoagulant. This high-purity active pharmaceutical ingredient (API) is critical for the development and manufacturing of life-saving antithrombotic medications. It is primarily required by pharmaceutical companies and research institutions engaged in cardiovascular drug development, clinical research, and generic API production.

Application

• Anticoagulant Drug Manufacturing: As the active pharmaceutical ingredient (API) in injectable formulations for the prevention and treatment of thrombosis.
• Heparin-Induced Thrombocytopenia (HIT) Treatment: A key therapeutic agent for patients with HIT who require parenteral anticoagulation.
• Percutaneous Coronary Intervention (PCI): Used as an anticoagulant in patients undergoing PCI, particularly those at risk for HIT.
• Cardiovascular Research: A vital tool for in vitro and in vivo studies investigating thrombin inhibition, blood coagulation pathways, and novel antithrombotic therapies.
• Reference Standard: Serves as a high-purity analytical standard for quality control testing in pharmaceutical laboratories.
• Formulation Development: Used in R&D for developing new drug delivery systems, generic formulations, and combination products.

Basic Information

Item	Detail
Product Name	Argatroban
CAS No.	141396-28-3
Molecular Formula	C23H36N6O5S
Molecular Weight	508.63 g/mol
Synonyms	Argatroban Monohydrate; (2R,4R)-4-Methyl-1-[N2-((RS)-3-methyl-1,2,3,4-tetrahydro-8-quinolinesulfonyl)-L-arginyl]-2-piperidinecarboxylic Acid; MD-805; Novastan; Slonnon; 2-Piperidinecarboxylic acid, 1-[5-[(aminoiminomethyl)amino]-1-oxo-2-[[(1,2,3,4-tetrahydro-3-methyl-8-quinolinyl)sulfonyl]amino]pentyl]-4-methyl-, (2R,4R)-; Argipidine
EINECS	Contact for details

Quality Control

Our Argatroban is manufactured under strict quality management systems. Each batch is tested to ensure it meets high-purity standards suitable for pharmaceutical applications, with comprehensive analytical methods including HPLC for assay and impurity profiling. A Certificate of Analysis (COA) is provided with each shipment, detailing specifications for identity, purity, related substances, residual solvents, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity: ≤ 0.5%; Total impurities: ≤ 2.0%
Heavy Metals	≤ 20 ppm
Microbial Enumeration	Meets Ph. Eur. / USP requirements

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.