Description

7-(3-Aminoazepan-1-Yl)-1-Cyclopropyl-6-Fluoro-4-Oxo-1,4-Dihydroquinoline-3-Carboxylic Acid is a high-purity advanced pharmaceutical intermediate (API intermediate) of significant commercial and research importance. This compound serves as a critical building block in the synthesis of novel fluoroquinolone antibiotics, enabling the development of next-generation antimicrobial agents. It is essential for pharmaceutical R&D laboratories, fine chemical manufacturers, and companies specializing in active pharmaceutical ingredient (API) production seeking reliable, high-quality raw materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of advanced fluoroquinolone antibiotic candidates.
• Antimicrobial Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies to develop new antibacterial agents.
• Active Pharmaceutical Ingredient (API) Manufacturing: Serves as a critical raw material in the multi-step production of target API molecules.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for specialized chemical entities.
• Biochemical Research: Utilized as a reference standard or probe in studies targeting bacterial DNA gyrase and topoisomerase IV.

Basic Information

Product Name	7-(3-Aminoazepan-1-Yl)-1-Cyclopropyl-6-Fluoro-4-Oxo-1,4-Dihydroquinoline-3-Carboxylic Acid
CAS No.	141388-65-0
Molecular Formula	C19H23FN4O3
Molecular Weight	374.41 g/mol
Synonyms	1-Cyclopropyl-6-fluoro-7-(3-aminoazepan-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; 7-(3-Amino-1-azepanyl)-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid; 141388-65-0; 7-(3-Aminoazepan-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; Fluoroquinolone intermediate; 3-Quinolinecarboxylic acid, 1,4-dihydro-7-(3-amino-1-azepanyl)-1-cyclopropyl-6-fluoro-4-oxo-
EINECS	Contact for details

Quality Control

Our 7-(3-Aminoazepan-1-Yl)-1-Cyclopropyl-6-Fluoro-4-Oxo-1,4-Dihydroquinoline-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.