Description

5-Bromo-2-(4-Methylpiperazin-1-Yl)Pyrimidine is a high-value heterocyclic organic compound featuring a pyrimidine core substituted with a bromine atom and a methylpiperazine moiety. This specific molecular architecture makes it a critical pharmaceutical intermediate and a versatile building block in advanced organic synthesis. It is primarily utilized by research institutions and chemical manufacturers engaged in the development of active pharmaceutical ingredients (APIs), particularly kinase inhibitors and other targeted therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, especially kinase inhibitors for oncology and other therapeutic areas.
• Organic Synthesis Building Block: Used in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and other transformations to construct more complex heterocyclic systems.
• Agrochemical Research: Serves as a starting material for developing novel crop protection agents and pesticides.
• Material Science: Potential monomer or precursor for creating specialty polymers and advanced functional materials.
• Biochemical Tool Compound: Used in life science research to study biological pathways and protein interactions.

Basic Information

Product Name	5-Bromo-2-(4-Methylpiperazin-1-Yl)Pyrimidine
CAS No.	141302-36-5
Molecular Formula	C9H12BrN5
Molecular Weight	270.13 g/mol
Synonyms	5-Bromo-2-(4-methyl-1-piperazinyl)pyrimidine; 2-(4-Methylpiperazin-1-yl)-5-bromopyrimidine; 5-Bromo-2-(4-methylpiperazin-1-yl)pyrimidine; 141302-36-5; 5-Bromo-2-(N-methylpiperazinyl)pyrimidine; 5-Bromo-2-(4-methylpiperazino)pyrimidine
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-(4-Methylpiperazin-1-Yl)Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent quality suitable for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.