Description

Boc-Tyr-Pro-Gly-Phe-Leu-Thr-Oh is a protected hexapeptide sequence featuring a tert-butyloxycarbonyl (Boc) N-terminal protecting group. This compound is a critical intermediate in solid-phase peptide synthesis (SPPS), enabling the controlled assembly of complex peptides and proteins. It is primarily utilized by research institutions and pharmaceutical companies engaged in peptide-based drug discovery, development of bioactive probes, and biochemical research.

Application

• Peptide Synthesis Intermediate: A key building block in the solid-phase synthesis of longer, more complex peptide sequences for research and development.
• Pharmaceutical R&D: Used in the discovery and development of novel therapeutic peptides targeting various diseases.
• Biochemical Research: Serves as a substrate or reference standard in enzymatic studies, receptor-ligand interaction assays, and structure-activity relationship (SAR) studies.
• Production of Bioactive Peptides: As a precursor for synthesizing peptides with potential hormonal, antimicrobial, or neurological activity.
• Custom Peptide Services: A fundamental component offered by CROs and CDMOs for producing client-specific peptide sequences.
• Academic Research: Employed in university laboratories for teaching advanced peptide chemistry and conducting fundamental life science research.

Basic Information

Product Name	Boc-Tyr-Pro-Gly-Phe-Leu-Thr-Oh
CAS No.	141261-96-3
Molecular Formula	C41H58N6O11
Molecular Weight	811.0 g/mol
Synonyms	Boc-Tyr-Pro-Gly-Phe-Leu-Thr-OH; Boc-Tyr-Pro-Gly-Phe-Leu-Thr; tert-Butyloxycarbonyl-Tyr-Pro-Gly-Phe-Leu-Thr; BOC-Y-P-G-F-L-T-OH; H-Tyr-Pro-Gly-Phe-Leu-Thr-OH BOC-protected; Hexapeptide BOC-YPGFLT; N-α-Boc-O-benzyl-L-tyrosyl-L-prolylglycyl-L-phenylalanyl-L-leucyl-L-threonine; Protected YPGFLT peptide
EINECS	Contact for details

Quality Control

Our Boc-Tyr-Pro-Gly-Phe-Leu-Thr-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and chiral analysis to ensure enantiomeric integrity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the exact specifications and test results. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, cool place. This product is hygroscopic (moisture-sensitive). Allow the sealed container to equilibrate to room temperature before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.