Description

Cyclo-Rgdphg CAS NO 141261-62-3 is a specialized cyclic peptide compound designed for high-affinity binding and targeted biological activity. This product is critical for researchers and developers requiring precise molecular tools for advanced life science applications. It serves as a key intermediate and active component in pharmaceutical R&D, particularly in the fields of oncology, targeted drug delivery, and diagnostic imaging.

Application

• Pharmaceutical Research & Development: As a potent integrin antagonist for developing novel anti-cancer and anti-angiogenic therapeutics.
• Targeted Drug Delivery Systems: Functionalization of nanoparticles, liposomes, and antibody-drug conjugates (ADCs) for site-specific delivery.
• Diagnostic Imaging Agents: Conjugation with radionuclides or fluorescent dyes for in vivo tumor targeting and visualization.
• Cell Biology & Biochemistry: A tool compound for studying cell adhesion, migration, and signaling pathways involving integrin receptors.
• Biomaterial Surface Modification: Coating of medical implants and scaffolds to promote specific cellular interactions and tissue integration.
• In Vitro Diagnostics (IVD): Component in assay kits for detecting specific cellular markers or pathological conditions.

Basic Information

Product Name	Cyclo-Rgdphg
CAS No.	141261-62-3
Molecular Formula	C28H44N10O8
Molecular Weight	648.71 g/mol
Synonyms	Cyclo(Arg-Gly-Asp-D-Phe-Hyp-Gly); c(RGDfK); Cyclo(RGDfK); Cyclic RGD Peptide; Cyclo(Arg-Gly-Asp-D-Phe-Hyp-Gly) acetate; Cyclo(RGDfK) acetate; c(RGDfK) acetate; Integrin αvβ3 antagonist (cyclic RGD)
EINECS	Contact for details

Quality Control

Our Cyclo-Rgdphg is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, MS for identity confirmation, and stringent controls for residual solvents and endotoxins. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to ensure traceability and compliance with your research or GMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Assay (HPLC)	≥ 98.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Acetate Content (IC)	5.0% - 15.0%
Single Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.