Description

n-Me-Ser-Oh·Hcl CAS NO 141193-65-9 is a protected serine derivative, specifically N-methyl-L-serine hydrochloride, serving as a critical chiral building block in advanced organic synthesis. Its value lies in providing a chemically modified serine scaffold that is essential for constructing complex peptide-based molecules and other bioactive compounds. This high-purity intermediate is primarily needed by pharmaceutical R&D laboratories, biotechnology companies, and fine chemical manufacturers engaged in the development of novel therapeutics, peptide hormones, and specialized agrochemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in oncology and metabolic disease research.
• Peptide Chemistry: Used in solid-phase and solution-phase peptide synthesis (SPPS) to incorporate modified serine residues, influencing peptide stability and bioactivity.
• Protecting Group Strategy: The N-methyl and hydrochloride salt form provides a protected amino acid handle for multi-step synthetic sequences, preventing unwanted side reactions.
• Bioconjugation & Probe Development: Serves as a starting material for creating labeled peptides or affinity probes used in biochemical assays and diagnostic research.
• Agrochemical Research: Employed in the design and synthesis of new peptide-mimetic fungicides or plant growth regulators.
• Academic & Process Chemistry: A valuable reagent for methodological development in asymmetric synthesis and for scaling up targeted molecular architectures.

Basic Information

Product Name	n-Me-Ser-Oh·Hcl
CAS No.	141193-65-9
Molecular Formula	C4H10ClNO3
Molecular Weight	155.58 g/mol
Synonyms	(S)-2-Amino-3-hydroxy-N-methylpropanoic acid hydrochloride; N-Methyl-L-serine hydrochloride; L-Serine, N-methyl-, hydrochloride (1:1); Methylserine hydrochloride; 3-Hydroxy-N-methylalanine hydrochloride; (2S)-2-(Methylamino)-3-hydroxypropanoic acid hydrochloride; H-N-Me-Ser-OH·HCl; N-Me-Ser-OH·HCl
EINECS	Contact for details

Quality Control

Our n-Me-Ser-Oh·Hcl is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and cGMP applications. Each lot undergoes comprehensive analytical testing, including chiral purity verification, to meet stringent customer specifications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, assay, impurity profile, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider desiccated environments.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.