Description

Silperisone is a pharmaceutical intermediate and active ingredient with the CAS registry number 140944-31-6. This compound is valued for its role in the synthesis of specialized therapeutic agents, particularly those targeting the central nervous system. It is primarily required by pharmaceutical manufacturers and advanced research institutions engaged in drug development and production.

Application

• Pharmaceutical Synthesis: Key intermediate in the production of centrally-acting muscle relaxants and spasmolytic agents.
• Active Pharmaceutical Ingredient (API): Used as the core active component in formulated drug products.
• Neurological Research: Serves as a critical compound in preclinical and clinical research for studying neuromuscular disorders.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and method validation in laboratories.
• Process Development: Employed in the scale-up and optimization of synthetic routes for new chemical entities (NCEs).

Basic Information

Product Name	Silperisone
CAS No.	140944-31-6
Molecular Formula	C₁₇H₂₄N₂O₂
Molecular Weight	288.39 g/mol
Synonyms	Silperisone; 1-(4-fluorophenyl)-2-methyl-3-(1-piperidinyl)-1-propanone; E-643; DA-398; DA 398; E 643; (RS)-Silperisone; (±)-Silperisone
EINECS	Contact for details

Quality Control

Our Silperisone is manufactured under strict quality management systems. We provide material suitable for pharmaceutical applications, with testing protocols aligned with ICH guidelines. A comprehensive Certificate of Analysis (COA) is provided with each batch, detailing purity, identity, and impurity profiles to ensure compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.