Description

Glycyl-Arginyl-Glycyl-Aspartyl-Seryl-Tyrosine is a synthetic hexapeptide with the sequence GRGDsY, designed to mimic key cell adhesion motifs found in extracellular matrix proteins. This compound matters for its high specificity in modulating integrin-mediated cell signaling, adhesion, and migration processes. It is primarily needed by researchers and developers in the pharmaceutical, biotechnology, and biomedical materials sectors for applications in drug discovery, tissue engineering, and advanced cell culture studies. The product is supplied as a high-purity, lyophilized powder to ensure consistent biological activity.

Application

• Biomedical Research: Used as a potent and selective inhibitor or promoter of integrin binding in cell adhesion and signaling studies.
• Drug Discovery: Serves as a lead compound or a biochemical tool for screening and developing novel therapeutics targeting integrin receptors.
• Tissue Engineering: Incorporated into scaffolds and biomaterials to promote specific cellular attachment and enhance tissue regeneration.
• Cell Culture: Coated on surfaces to create defined, bioactive substrates for improved cell growth and differentiation in vitro.
• Diagnostic Development: Utilized in the design of assays and biosensors to detect integrin expression or activity.
• Bioconjugation: Acts as a targeting ligand for the functionalization of nanoparticles, drug delivery systems, and imaging agents.

Basic Information

Product Name	Glycyl-Arginyl-Glycyl-Aspartyl-Seryl-Tyrosine
CAS No.	140457-22-3
Molecular Formula	C29H45N11O12
Molecular Weight	739.74 g/mol
Synonyms	GRGDsY; GRGDsY Peptide; Gly-Arg-Gly-Asp-Ser-Tyr; GRGDSY; Adhesion Peptide GRGDsY; Arg-Gly-Asp-Ser-Tyr Peptide; Hexapeptide GRGDsY; GRGDsY-OH
EINECS	Contact for details

Quality Control

Our Glycyl-Arginyl-Glycyl-Aspartyl-Seryl-Tyrosine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. For long-term storage, keep desiccated under inert atmosphere. The product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80%
Solubility	Soluble in water or buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.