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H-Ser-Phe-Phe-Leu-Arg-Asn-Oh Trifluoroacetate CAS NO 140436-67-5


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CAS No.:140436-67-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

H-Ser-Phe-Phe-Leu-Arg-Asn-Oh Trifluoroacetate is a high-purity synthetic peptide derivative, specifically a heptapeptide amide with a trifluoroacetate salt counterion. This compound is a critical intermediate and research tool for advanced biochemical studies and pharmaceutical development. It is primarily utilized by research institutions and pharmaceutical companies engaged in peptide synthesis, structure-activity relationship (SAR) studies, and the development of novel therapeutic agents.

Application

  • Pharmaceutical Research & Development: Serves as a key intermediate in the synthesis of complex peptide-based drug candidates and for investigating biological pathways.
  • Biochemical Assay Development: Used as a standard or substrate in enzymatic assays to study protease activity and inhibition.
  • Structure-Activity Relationship (SAR) Studies: Essential for modifying peptide sequences to optimize binding affinity, stability, and pharmacological properties.
  • Peptide Library Construction: A building block for creating combinatorial peptide libraries used in high-throughput screening for drug discovery.
  • Academic Research: Employed in university and institutional labs for fundamental research in biochemistry, molecular biology, and medicinal chemistry.
  • Reference Standard: Functions as a certified reference material (CRM) for quality control and analytical method validation in GLP/GMP environments.

Basic Information

Product Name H-Ser-Phe-Phe-Leu-Arg-Asn-Oh Trifluoroacetate
CAS No. 140436-67-5
Molecular Formula C44H62N10O11 • C2HF3O2
Molecular Weight Contact for details
Synonyms H-Ser-Phe-Phe-Leu-Arg-Asn-NH2 TFA; Ser-Phe-Phe-Leu-Arg-Asn-Amide TFA Salt; Heptapeptide Amide SFFLRN-NH2 • TFA; SFLLRN-NH2 analog; PAR-1 (Protease-Activated Receptor 1) agonist-related peptide; Thrombin receptor agonist peptide (TRAP) derivative; H-Ser-Phe-Phe-Leu-Arg-Asn-NH2 x CF3COOH
EINECS Contact for details

Quality Control

Our H-Ser-Phe-Phe-Leu-Arg-Asn-Oh Trifluoroacetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and tests for residual solvents and moisture content, to ensure it meets the stringent requirements for research and development. Certificates of Analysis (COA) with detailed chromatographic data are available for every lot to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, cool place. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item Specification
Appearance White to off-white powder
Identification (HPLC/MS) Conforms
Purity (HPLC) ≥ 95.0%
Single Impurity (HPLC) ≤ 1.0%
Water Content (KF) ≤ 5.0%
Peptide Content ≥ 70.0%
Acetate Content (HPLC) Conforms

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.

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