Description

Fmoc-Dap(Fmoc)-Oh is a specialized, high-purity amino acid derivative used as a critical building block in solid-phase peptide synthesis (SPPS). This compound matters because it provides orthogonal protection for the side chain of diaminopropionic acid, enabling the precise and sequential construction of complex peptides. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors who are developing peptide-based therapeutics, diagnostic agents, and research biochemicals.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected amino acid for the automated synthesis of peptides containing diaminopropionic acid residues.
• Pharmaceutical Intermediates: Used in the research and development of novel peptide drugs, including antimicrobial peptides and hormone analogs.
• Bioconjugation: Serves as a linker or spacer molecule for attaching peptides to other biomolecules, surfaces, or carriers.
• Chemical Biology Research: Employed in the study of protein-protein interactions and the design of peptide inhibitors or probes.
• Combinatorial Chemistry: A valuable component in libraries for high-throughput screening of bioactive peptide sequences.
• API Development: Used in the process development and scale-up of Active Pharmaceutical Ingredients (APIs) with specific structural requirements.

Basic Information

Product Name	Fmoc-Dap(Fmoc)-Oh
CAS No.	140430-54-2
Molecular Formula	C33H28N2O6
Molecular Weight	548.59 g/mol
Synonyms	Fmoc-Dap(Fmoc)-OH; Nα,Nβ-Bis(9-fluorenylmethoxycarbonyl)-L-2,3-diaminopropionic acid; (2S)-2,3-Bis{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}propanoic acid; Fmoc-Dap(Fmoc)-OH; Fmoc-L-Dap(Fmoc)-OH; Nα-Fmoc-Nβ-Fmoc-L-2,3-diaminopropanoic acid; L-Dap(Boc) derivative (protected form); Fmoc-Dap(Fmoc)
EINECS	Contact for details

Quality Control

Our Fmoc-Dap(Fmoc)-Oh is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for sensitive peptide synthesis applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.