Description

2-Benzofurancarboxaldehyde, 5-Fluoro- is a high-purity fluorinated benzofuran derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in the strategic incorporation of fluorine, which can dramatically alter the physicochemical and biological properties of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients with enhanced efficacy and stability.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in developing new-generation herbicides, fungicides, and insecticides where the fluorine atom improves lipophilicity and metabolic stability.
• Material Science: Serves as a precursor for specialty polymers, liquid crystals, and organic electronic materials requiring specific fluorinated aromatic units.
• Organic Synthesis: A versatile reagent for constructing complex heterocyclic frameworks via reactions at the aldehyde functional group.
• Fluorine Chemistry Studies: Used as a model compound in academic and industrial research to study structure-activity relationships (SAR) influenced by fluorine substitution.

Basic Information

Product Name	2-Benzofurancarboxaldehyde, 5-Fluoro-
CAS No.	140382-35-0
Molecular Formula	C9H5FO2
Molecular Weight	164.13 g/mol
Synonyms	5-Fluoro-2-benzofurancarboxaldehyde; 5-Fluorobenzofuran-2-carbaldehyde; 5-Fluoro-1-benzofuran-2-carboxaldehyde; 5-Fluoro-2-formylbenzofuran; 5-Fluorobenzo[b]furan-2-carboxaldehyde; 2-Benzofurancarboxaldehyde, 5-fluoro-; 140382-35-0
EINECS	Contact for details

Quality Control

Every batch of 5-Fluoro-2-benzofurancarboxaldehyde is manufactured under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee it meets your precise research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.