Description

S-D-Dithiomandeloylglutathione is a specialized, high-purity biochemical compound designed for advanced research and pharmaceutical development. This modified glutathione derivative is critical for studies involving redox biology, enzyme inhibition, and the development of novel therapeutic agents. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies focused on metabolic pathways, antioxidant defense systems, and targeted drug discovery.

Application

• Biochemical Research: Used as a key reagent in studying glutathione metabolism, redox signaling, and thiol-disulfide exchange mechanisms.
• Enzyme Inhibition Studies: Acts as a potential inhibitor or substrate analog for enzymes like glutathione S-transferases (GSTs) and other glutathione-dependent enzymes.
• Pharmaceutical Development: Serves as a building block or intermediate in the synthesis of novel drug candidates targeting oxidative stress-related diseases.
• Proteomics & Cell Biology: Employed in experiments to probe protein S-thiolation, glutathionylation, and other post-translational modifications.
• Reference Standard: Used as a certified reference material (CRM) for analytical method development and validation in quality control laboratories.

Basic Information

Product Name	S-D-Dithiomandeloylglutathione
CAS No.	140234-19-1
Molecular Formula	C20H28N4O9S3
Molecular Weight	564.65 g/mol
Synonyms	Glutathione, S-(dithiomandeloyl)-; S-(Dithiomandeloyl)glutathione; Dithiomandeloyl Glutathione; γ-Glu-Cys(S-S-CH(Ph)COOH)-Gly; (2S)-2-Amino-5-[[(2R)-1-[(carboxymethyl)amino]-3-[[(2R)-2-[[(2R)-2-amino-3-sulfanylpropanoyl]amino]-3-oxo-3-(phenylmethoxy)propanoyl]disulfanyl]-1-oxopropan-2-yl]amino]-5-oxopentanoic acid
EINECS	Contact for details

Quality Control

Every batch of S-D-Dithiomandeloylglutathione is manufactured under strict quality management systems. We provide comprehensive analytical documentation to ensure product integrity and traceability. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot and supplied upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label. This material is easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as argon or nitrogen. Keep the container in a dry, cool, and well-ventilated area.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.