Description

4-Carboxymethylphenylalanine is a high-purity, non-natural amino acid derivative featuring a carboxymethyl group on the phenyl ring. This compound is a critical chiral building block and intermediate in advanced organic synthesis, particularly for the development of novel pharmaceuticals and bioactive peptides. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors requiring precise molecular scaffolds for drug discovery and development.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of protease inhibitors, enzyme inhibitors, and other active pharmaceutical ingredients (APIs).
• Peptide Chemistry: Used in solid-phase and solution-phase peptide synthesis to incorporate modified phenylalanine residues, enhancing peptide stability and bioactivity.
• Bioconjugation & Linker Chemistry: Serves as a versatile building block for creating drug-linker systems in antibody-drug conjugates (ADCs) and other targeted therapies.
• Chemical Biology Research: Employed as a tool compound or labeled analog in biochemical assays and metabolic pathway studies.
• Fine Chemical Synthesis: Acts as a precursor for complex organic molecules, including specialty polymers and advanced materials with specific functional properties.

Basic Information

Product Name	4-Carboxymethylphenylalanine
CAS No.	140233-60-9
Molecular Formula	C11H13NO4
Molecular Weight	223.23 g/mol
Synonyms	4-(Carboxymethyl)-L-phenylalanine; (2S)-2-Amino-3-[4-(carboxymethyl)phenyl]propanoic acid; Fmoc-4-Carboxymethyl-L-phenylalanine; 4-Carboxymethyl-L-Phe-OH; 4-(Carboxymethyl)phenylalanine; 4-CMP; 4-Carboxymethyl-Phe
EINECS	Contact for details

Quality Control

Our 4-Carboxymethylphenylalanine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and spectroscopic identification, to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.