Description

tert-Butyl 3-Methyl-1-Oxobutan-2-Ylcarbamate is a high-purity chemical intermediate characterized by its specific carbamate and ketone functional groups. This compound is valued for its role as a versatile building block in the synthesis of more complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of active pharmaceutical ingredients (APIs), especially those requiring protected amine functionalities.
• Peptide Synthesis: Used in the preparation of non-natural amino acid derivatives and as a protecting group reagent in solid-phase and solution-phase peptide chemistry.
• Agrochemical Research: Serves as a precursor in the development of new herbicides, fungicides, and plant growth regulators.
• Organic Synthesis Building Block: Employed in academic and industrial laboratories for the construction of complex heterocycles and other specialty organic compounds.
• Material Science: Potential use in the synthesis of monomers for specialized polymers and advanced functional materials.

Basic Information

Product Name	tert-Butyl 3-Methyl-1-Oxobutan-2-Ylcarbamate
CAS No.	140171-27-3
Molecular Formula	C10H19NO3
Molecular Weight	201.26 g/mol
Synonyms	2-[(tert-Butoxycarbonyl)amino]-3-methylbutanoic acid; Boc-3-methyl-DL-norvaline; N-Boc-3-methylnorvaline; tert-Butyl (3-methyl-1-oxobutan-2-yl)carbamate; 2-((tert-Butoxycarbonyl)amino)-3-methylbutanoic acid; N-(tert-Butoxycarbonyl)-3-methylnorvaline; BOC-3-Me-Nva-OH
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-Methyl-1-Oxobutan-2-Ylcarbamate is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure it meets the highest standards of purity and consistency required for research and production. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.