Description

Hippocampal Cholinergic Neurostimulating Peptide (HCNP) is a bioactive undecapeptide that plays a crucial role in the development and function of the central cholinergic nervous system. This compound is of significant interest for its neurotrophic and neuroprotective properties, influencing cholinergic neuron differentiation and survival. It serves as a critical research tool for neuroscientists and pharmaceutical developers investigating neurodegenerative diseases, cognitive function, and neurodevelopmental disorders.

Application

• Neuroscience Research: A key reagent for studying cholinergic system development, synaptic plasticity, and neuronal signaling pathways in vitro and in vivo.
• Drug Discovery & Development: Used as a reference standard and active pharmaceutical ingredient (API) in preclinical studies for Alzheimer's disease, dementia, and other cognitive disorders.
• Biochemical Assays: Employed in enzyme-linked immunosorbent assays (ELISAs), receptor binding studies, and functional cellular assays to investigate its mechanism of action.
• Academic & Institutional Research: Essential for universities and research institutes exploring neurotrophic factors, neuroprotection, and neural regeneration.
• Peptide Therapeutics R&D: Serves as a lead compound or structural template for developing novel peptide-based neurotherapeutic agents.
• Diagnostic Development: Potential use in developing biomarkers or diagnostic tools related to cholinergic dysfunction.

Basic Information

Product Name	Hippocampal Cholinergic Neurostimulating Peptide
CAS No.	140158-49-2
Molecular Formula	C58H86N16O16
Molecular Weight	1247.4 g/mol
Synonyms	HCNP; Hippocampal Cholinergic Neurostimulating Peptide; HCNP Precursor Peptide; Arg-Pro-Leu-Pro-Leu-Pro-Gln-Gly-Gly-Ser-Arg; Hippocampal Peptide; Cholinergic Neuron-Stimulating Peptide; Neurotrophic Peptide HCNP; Undecapeptide HCNP
EINECS	Contact for details

Quality Control

Our Hippocampal Cholinergic Neurostimulating Peptide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with research-grade material standards. We support cGMP-compliant production for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and easily oxidized; for long-term storage, consider under an inert atmosphere such as argon or nitrogen. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Composition	Conforms to theoretical values
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80%
Solubility	Soluble in water, dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.