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N(Epsilon)-(1-Deoxyfructos-1-Yl)Hippuryllysine CAS NO 139950-87-1
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CAS No.:139950-87-1
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
N(Epsilon)-(1-Deoxyfructos-1-Yl)Hippuryllysine is a specific advanced glycation end-product (AGE) derived from the Maillard reaction between hippuryllysine and fructose. This compound is of significant interest as a biomarker and reference standard for research into metabolic disorders, diabetes, and aging processes. It is primarily utilized by research institutions, diagnostic kit manufacturers, and pharmaceutical R&D laboratories for analytical method development and biochemical studies.
Application
- Biochemical Research: Used as a critical reference standard in studies investigating the formation, metabolism, and pathological effects of advanced glycation end-products (AGEs).
- Diagnostic Development: Serves as a calibration standard for the development and validation of immunoassays (ELISA) and chromatographic methods (HPLC, LC-MS/MS) aimed at detecting AGEs in biological samples.
- Pharmaceutical R&D: Employed in screening and efficacy testing of potential therapeutic agents designed to inhibit AGE formation or break AGE cross-links.
- Nutritional Science: Used in research models to study the impact of dietary sugars and the Maillard reaction in food on in vivo glycation processes.
- Quality Control: Acts as a high-purity standard for ensuring the accuracy and reliability of analytical results in contract research organizations (CROs) and testing laboratories.
Basic Information
| Product Name | N(Epsilon)-(1-Deoxyfructos-1-Yl)Hippuryllysine |
| CAS No. | 139950-87-1 |
| Molecular Formula | C22H31N3O9 |
| Molecular Weight | 481.50 g/mol |
| Synonyms | Nε-(1-Deoxyfructos-1-yl)hippuryllysine; Nε-Hippuryl-Nε-(1-deoxy-D-fructos-1-yl)-L-lysine; Hippuryl-lysine fructosamine; AGE-Hippuryllysine; Fructosamine derivative of hippuryllysine; Maillard reaction product of hippuryllysine; Nε-(1-Deoxy-D-fructos-1-yl)-Nα-hippuryl-L-lysine |
| EINECS | Contact for details |
Quality Control
Our N(Epsilon)-(1-Deoxyfructos-1-Yl)Hippuryllysine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical characterization, including HPLC purity analysis, mass spectrometry (MS) for identity confirmation, and NMR spectroscopy. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade standards. Our quality system supports the needs of GMP/GLP-compliant laboratories.
Storage
Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake. For long-term storage, consider under an inert atmosphere.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (HPLC) | Conforms to reference standard |
| Identification (MS) | Conforms to structure |
| Purity (HPLC) | ≥ 95.0% |
| Water Content (KF) | ≤ 5.0% |
| Solubility | Soluble in water, DMSO |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.
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