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N(Epsilon)-(1-Deoxyfructos-1-Yl)Hippuryllysine CAS NO 139950-87-1


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CAS No.:139950-87-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

N(Epsilon)-(1-Deoxyfructos-1-Yl)Hippuryllysine is a specific advanced glycation end-product (AGE) derived from the Maillard reaction between hippuryllysine and fructose. This compound is of significant interest as a biomarker and reference standard for research into metabolic disorders, diabetes, and aging processes. It is primarily utilized by research institutions, diagnostic kit manufacturers, and pharmaceutical R&D laboratories for analytical method development and biochemical studies.

Application

  • Biochemical Research: Used as a critical reference standard in studies investigating the formation, metabolism, and pathological effects of advanced glycation end-products (AGEs).
  • Diagnostic Development: Serves as a calibration standard for the development and validation of immunoassays (ELISA) and chromatographic methods (HPLC, LC-MS/MS) aimed at detecting AGEs in biological samples.
  • Pharmaceutical R&D: Employed in screening and efficacy testing of potential therapeutic agents designed to inhibit AGE formation or break AGE cross-links.
  • Nutritional Science: Used in research models to study the impact of dietary sugars and the Maillard reaction in food on in vivo glycation processes.
  • Quality Control: Acts as a high-purity standard for ensuring the accuracy and reliability of analytical results in contract research organizations (CROs) and testing laboratories.

Basic Information

Product Name N(Epsilon)-(1-Deoxyfructos-1-Yl)Hippuryllysine
CAS No. 139950-87-1
Molecular Formula C22H31N3O9
Molecular Weight 481.50 g/mol
Synonyms Nε-(1-Deoxyfructos-1-yl)hippuryllysine; Nε-Hippuryl-Nε-(1-deoxy-D-fructos-1-yl)-L-lysine; Hippuryl-lysine fructosamine; AGE-Hippuryllysine; Fructosamine derivative of hippuryllysine; Maillard reaction product of hippuryllysine; Nε-(1-Deoxy-D-fructos-1-yl)-Nα-hippuryl-L-lysine
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Quality Control

Our N(Epsilon)-(1-Deoxyfructos-1-Yl)Hippuryllysine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical characterization, including HPLC purity analysis, mass spectrometry (MS) for identity confirmation, and NMR spectroscopy. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade standards. Our quality system supports the needs of GMP/GLP-compliant laboratories.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item Specification
Appearance White to off-white powder
Identification (HPLC) Conforms to reference standard
Identification (MS) Conforms to structure
Purity (HPLC) ≥ 95.0%
Water Content (KF) ≤ 5.0%
Solubility Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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