Description

4-Amino-L-Phenylalanine, Dihydrochloride is a high-purity, protected amino acid derivative essential for advanced peptide synthesis and pharmaceutical research. This compound serves as a critical building block for creating complex molecules with specific biological activities. It is primarily utilized by research institutions, pharmaceutical developers, and fine chemical manufacturers working on novel therapeutics, diagnostic agents, and biochemical tools.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to incorporate the 4-aminophenylalanine moiety into peptide chains.
• Bioconjugation & Labeling: The aromatic amine group provides a reactive handle for conjugation with fluorescent dyes, biotin, or other probes for diagnostic and research applications.
• Chemical Biology Research: Employed in the study of enzyme mechanisms, receptor-ligand interactions, and the development of enzyme inhibitors.
• Material Science: Potential use in the development of functionalized polymers and smart biomaterials.

Basic Information

Product Name	4-Amino-L-Phenylalanine, Dihydrochloride
CAS No.	139879-21-3
Molecular Formula	C9H14Cl2N2O2
Molecular Weight	253.13 g/mol
Synonyms	L-4-Aminophenylalanine dihydrochloride; (2S)-2-Amino-3-(4-aminophenyl)propanoic acid dihydrochloride; 4-Amino-DL-phenylalanine dihydrochloride (related); Phenylalanine, 4-amino-, dihydrochloride, L-; H-Phe(4-NH2)-OH·2HCl; Fmoc-Phe(4-NH2)-OH·2HCl (protected form); 4-Amino-L-Phe-OH·2HCl
EINECS	Contact for details

Quality Control

Our 4-Amino-L-Phenylalanine, Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the stringent requirements for research and pharmaceutical development. A Certificate of Analysis (COA) detailing purity, identity, and specific tests is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider desiccated or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (L-isomer)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.