Description

5-Bromo-L-Tryptophan Hydrochloride is a halogenated derivative of the essential amino acid L-tryptophan, serving as a critical chiral building block and biochemical precursor. This compound is valued for its role in the synthesis of complex molecules and its utility in advanced research applications. It is primarily sought by pharmaceutical R&D teams, biotechnology companies, and academic institutions engaged in medicinal chemistry, peptide synthesis, and neurochemical studies.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly those targeting neurological pathways.
• Peptide Synthesis: Used for the site-specific incorporation of brominated tryptophan analogs into synthetic peptides and proteins for structure-activity relationship (SAR) studies.
• Biochemical Research: Serves as a precursor or standard in metabolic studies, enzyme-substrate interaction assays, and proteomics research.
• Medicinal Chemistry: Employed in the design and synthesis of drug candidates, where the bromine atom allows for further functionalization via cross-coupling reactions.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for HPLC, LC-MS, or NMR method development and validation.

Basic Information

Product Name	5-Bromo-L-Tryptophan Hydrochloride
CAS No.	139684-34-7
Molecular Formula	C₁₁H₁₂BrN₂O₂·HCl
Molecular Weight	321.59 g/mol
Synonyms	(S)-2-Amino-3-(5-bromo-1H-indol-3-yl)propanoic acid hydrochloride; 5-Bromo-L-tryptophan HCl; 5-Br-L-Trp·HCl; 5-Bromotryptophan hydrochloride (L-form); H-5-Br-Trp-OH·HCl; 5-Bromo-1H-indole-3-propanoic acid, α-amino-, hydrochloride, (αS)-; L-α-Amino-1H-indole-3-propanoic acid, 5-bromo-, monohydrochloride
EINECS	Contact for details

Quality Control

Our 5-Bromo-L-Tryptophan Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing specifications such as assay, enantiomeric excess, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Purity (HPLC)	≥99.0% (L-isomer)
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.