Description

Dnp-Pro-Glu-Ala-Asn-Nh2 is a synthetic peptide derivative featuring a dinitrophenyl (Dnp) protecting group. This compound is a critical intermediate in advanced peptide synthesis and biochemical research, valued for its role in studying enzyme kinetics and protein-protein interactions. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions focused on proteomics and medicinal chemistry.

Application

• Peptide Synthesis Intermediate: Serves as a key building block in the solid-phase and solution-phase synthesis of longer, complex peptide sequences.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly for proteases and transferases, to elucidate biological mechanisms.
• Proteomics & Labeling Studies: The Dnp group acts as a chromophore or a tag for detection, purification, and analysis in mass spectrometry and chromatography.
• Medicinal Chemistry: Employed in the design and development of novel therapeutic peptides and peptidomimetics by providing a protected intermediate.
• Antibody Production: Can be conjugated to carrier proteins to generate specific antibodies for immunoassays and diagnostic applications.

Basic Information

Product Name	Dnp-Pro-Glu-Ala-Asn-Nh2
CAS No.	139554-33-9
Molecular Formula	C24H31N7O12
Molecular Weight	585.55 g/mol
Synonyms	Dnp-Pro-Glu-Ala-Asn-amide; N-2,4-Dinitrophenyl-L-prolyl-L-α-glutamyl-L-alanyl-L-asparaginamide; DNP-P-E-A-N-NH2; 2,4-DNP-Pro-Glu-Ala-Asn-NH2; L-Prolyl-N-(2,4-dinitrophenyl)-L-α-glutamyl-L-alanyl-L-asparaginamide; Dnp-Protected Tetrapeptide Amide; CAS 139554-33-9
EINECS	Contact for details

Quality Control

Our Dnp-Pro-Glu-Ala-Asn-Nh2 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via mass spectrometry. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain purity and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.