Description

Phenol, 2-Amino-3,6-Difluoro- (9Ci) is a fluorinated aminophenol derivative, a high-value intermediate prized for its unique molecular architecture. This compound matters for its role as a critical building block in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where its fluorine atoms and phenolic group enable precise chemical modifications. It is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel compounds with enhanced properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides and pesticides, where the fluorine atoms improve biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorine-containing compounds used in electronic display technologies.
• Polymer Modification: Acts as a monomer or additive to introduce fluorine and amine functionality into polymers, enhancing thermal and chemical resistance.
• Dye & Pigment Manufacturing: Employed in the synthesis of specialized fluorinated dyes and colorants.
• Cross-coupling Reactions: A valuable substrate in Suzuki, Buchwald-Hartwig, and other palladium-catalyzed coupling reactions for complex molecule assembly.
• Research & Development: Used in academic and industrial labs for exploratory chemistry and process development.

Basic Information

Product Name	Phenol, 2-Amino-3,6-Difluoro- (9Ci)
CAS No.	139548-98-4
Molecular Formula	C6H5F2NO
Molecular Weight	145.11 g/mol
Synonyms	2-Amino-3,6-difluorophenol; 3,6-Difluoro-2-aminophenol; 2-Amino-3,6-difluoro-1-hydroxybenzene; 1-Hydroxy-2-amino-3,6-difluorobenzene; 3,6-Difluoro-2-hydroxyaniline; 2-Hydroxy-3,6-difluoroaniline; 2-Amino-3,6-difluorophenol (9CI)
EINECS	Contact for details

Quality Control

Our Phenol, 2-Amino-3,6-Difluoro- (9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.