Description

2,5-Difluoro-6-Nitrophenol is a versatile fluorinated aromatic intermediate of significant importance in advanced organic synthesis. Its unique structure, featuring both electron-withdrawing nitro and fluoro substituents on a phenolic core, makes it a critical building block for constructing complex molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, pesticides, and fungicides, where the fluorine atoms enhance biological activity and stability.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers, liquid crystals, and advanced organic electronic materials.
• Dye and Pigment Industry: Acts as an intermediate for synthesizing specialized fluorinated dyes and pigments with unique color fastness and spectral properties.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D in organic chemistry, facilitating studies on nucleophilic aromatic substitution and cross-coupling reactions.

Basic Information

Product Name	2,5-Difluoro-6-Nitrophenol
CAS No.	139548-97-3
Molecular Formula	C6H3F2NO3
Molecular Weight	175.09 g/mol
Synonyms	2,5-Difluoro-6-nitro-1-phenol; 6-Nitro-2,5-difluorophenol; Phenol, 2,5-difluoro-6-nitro-; 2,5-Difluoro-6-nitrophenol; 1-Hydroxy-2,5-difluoro-6-nitrobenzene
EINECS	Contact for details

Quality Control

Every batch of 2,5-Difluoro-6-Nitrophenol is manufactured and tested under a strict quality management system to ensure consistency and reliability for your critical processes. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles as determined by advanced analytical techniques. Our quality commitment aligns with cGMP principles where applicable, ensuring traceability and documentation for regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.