Description

5-Cyano-Dl-Tryptophan is a synthetic, non-natural amino acid derivative featuring a cyano group at the 5-position of the indole ring. This modification makes it a valuable specialty building block and research chemical for advanced organic synthesis and biochemical studies. It is primarily utilized by pharmaceutical R&D teams, peptide chemists, and academic researchers developing novel bioactive compounds and molecular probes.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting neurological pathways.
• Peptide Chemistry & Modification: Used to incorporate a unique, chemically reactive cyano-tryptophan moiety into synthetic peptides for structure-activity relationship (SAR) studies.
• Biochemical Research: Acts as a probe or inhibitor in enzymatic studies, leveraging its modified indole structure to investigate protein function and binding sites.
• Fluorescent Probe Development: The cyano group can influence the photophysical properties of the tryptophan chromophore, making it useful in developing new fluorescent labels.
• Academic & Contract Research: Essential for universities and CROs (Contract Research Organizations) conducting cutting-edge research in medicinal chemistry and chemical biology.

Basic Information

Product Name	5-Cyano-Dl-Tryptophan
CAS No.	139393-02-5
Molecular Formula	C₁₂H₁₁N₃O₂
Molecular Weight	229.24 g/mol
Synonyms	5-Cyano-DL-tryptophan; DL-5-Cyanotryptophan; 2-Amino-3-(5-cyano-1H-indol-3-yl)propanoic acid; (±)-5-Cyanotryptophan; 5-CN-DL-Trp; 5-Cyano-DL-Trp; 5-Cyano-DL-tryptophane; 5-Cyano-DL-α-amino-1H-indole-3-propanoic acid
EINECS	Contact for details

Quality Control

Our 5-Cyano-Dl-Tryptophan is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, IR, MS), to ensure it meets exacting research and development standards. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and specification compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is moisture-sensitive (hygroscopic); ensure the container is kept sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.