Description

n-Acetyl-S-Geranylgeranyl-L-Cysteine is a specialized, prenylated cysteine derivative that serves as a crucial biochemical tool and synthetic intermediate. This compound is valued for its role in studying protein prenylation, a key post-translational modification involved in membrane association and signaling pathways. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life science research sectors for developing novel therapeutics and conducting mechanistic studies.

Application

• Biochemical Research: A key substrate and reference standard for investigating protein prenylation enzymes like geranylgeranyltransferases.
• Pharmaceutical Development: Serves as a critical intermediate in the synthesis of prenylation inhibitors and other targeted therapeutic agents.
• Enzymology Studies: Used to assay and characterize the activity of Rab geranylgeranyltransferase (GGTase) and related enzymes.
• Cell Signaling Research: Employed in studies of Ras superfamily GTPase function, where geranylgeranylation is essential for membrane localization and activity.
• Standards and Metabolites: Acts as a high-purity analytical standard for metabolite identification and quantification in biological samples.
• Chemical Synthesis: A versatile building block for the preparation of more complex prenylated peptides and biomimetic compounds.

Basic Information

Product Name	n-Acetyl-S-Geranylgeranyl-L-Cysteine
CAS No.	139332-94-8
Molecular Formula	C₂₇H₄₅NO₃S
Molecular Weight	463.72 g/mol
Synonyms	N-Acetyl-S-geranylgeranyl-L-cysteine; N-Acetyl-S-(all-trans-geranylgeranyl)-L-cysteine; Acetyl-GGC; Ac-GGC-OH; S-Geranylgeranyl-N-acetylcysteine; (2R)-2-Acetamido-3-[[(2E,6E,10E)-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraen-1-yl]sulfanyl]propanoic acid
EINECS	Contact for details

Quality Control

Our n-Acetyl-S-Geranylgeranyl-L-Cysteine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥95.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.