Description

ω-n-Cyclopropylarginine is a non-proteinogenic, cyclopropyl-modified derivative of the essential amino acid L-arginine. This specialized compound is of significant interest in advanced biochemical research and pharmaceutical development due to its unique structural modification, which can impart distinct biological activity and metabolic stability. It serves as a critical building block and research tool for scientists in medicinal chemistry, peptide synthesis, and enzymology.

Application

• Medicinal Chemistry & Drug Discovery: Used as a constrained arginine analog for structure-activity relationship (SAR) studies to develop novel enzyme inhibitors and receptor modulators.
• Peptide Synthesis & Modification: Incorporated into synthetic peptides to enhance stability, alter conformation, or probe protein-protein interactions.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic assays, particularly for nitric oxide synthase (NOS) and other arginine-processing enzymes.
• Pharmaceutical Intermediates: Acts as a key chiral synthon in the multi-step synthesis of potential therapeutic agents targeting cardiovascular and neurological pathways.
• Academic & Institutional Research: A valuable tool for studying amino acid transport, metabolism, and the role of arginine derivatives in cellular signaling.

Basic Information

Product Name	ω-n-Cyclopropylarginine
CAS No.	139299-32-4
Molecular Formula	C9H18N4O2
Molecular Weight	214.27 g/mol
Synonyms	Nω-Cyclopropyl-L-arginine; (S)-2-Amino-5-[(cyclopropylamino)imino]pentanoic acid; Cyclopropylarginine; L-Nω-Cyclopropylarginine; NG-Cyclopropyl-L-arginine; ω-Cyclopropyl-L-arginine; 139299-32-4
EINECS	Contact for details

Quality Control

Our ω-n-Cyclopropylarginine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via spectroscopic methods. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research specifications. Our quality commitment supports applications requiring high-purity, well-characterized biochemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Optical Rotation	[α]D20: Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.