Description

4-Fluoro-2-(Trifluoromethyl)Aniline Hydrochloride is a high-purity, halogenated aniline derivative salt, serving as a critical building block in advanced organic synthesis. Its value lies in the unique combination of fluorine and trifluoromethyl groups, which are instrumental in modulating the lipophilicity, metabolic stability, and binding affinity of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated aromatic components for electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer Chemistry: Acts as a monomer or modifier in the creation of specialty polymers with enhanced chemical resistance, thermal stability, and surface properties.
• Dye & Pigment Manufacturing: Employed in the synthesis of complex, high-performance dyes and pigments for specialized industrial applications.
• Chemical Research & Development: A versatile reagent for exploring new reaction pathways and creating novel fluorinated compounds in academic and industrial R&D labs.

Basic Information

Product Name	4-Fluoro-2-(Trifluoromethyl)Aniline Hydrochloride
CAS No.	139291-82-0
Molecular Formula	C7H5ClF4N
Molecular Weight	223.57 g/mol
Synonyms	2-Amino-5-fluorobenzotrifluoride Hydrochloride; 4-Fluoro-2-(trifluoromethyl)benzenamine Hydrochloride; 5-Fluoro-α,α,α-trifluoro-o-toluidine Hydrochloride; 2-Trifluoromethyl-4-fluoroaniline Hydrochloride; 4-Fluoro-α,α,α-trifluoro-o-toluidine Hydrochloride; 1-Amino-4-fluoro-2-(trifluoromethyl)benzene Hydrochloride; Benzenamine, 4-fluoro-2-(trifluoromethyl)-, hydrochloride
EINECS	Contact for details

Quality Control

Every batch of 4-Fluoro-2-(Trifluoromethyl)Aniline Hydrochloride undergoes rigorous analytical testing to ensure it meets the high-purity standards required for sensitive synthetic applications. Our quality assurance protocol includes advanced chromatographic and spectroscopic methods. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under anhydrous conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.