Description

Nazumamide A CAS NO 138949-86-7 is a specialized cyclic depsipeptide compound of significant interest in advanced life science research. Its unique molecular structure, featuring a rare 3-amino-6-hydroxy-2-piperidone (Ahp) unit, makes it a valuable tool for studying biological pathways and interactions. This compound is primarily utilized by researchers and developers in the pharmaceutical and biotechnology sectors for high-value applications such as target validation and biochemical mechanism elucidation.

Application

• Biochemical Research: Serves as a key reference standard and investigative tool in proteomics and enzymology studies.
• Pharmaceutical Development: Used as a lead compound or molecular scaffold in the discovery of novel therapeutic agents, particularly for oncology and infectious diseases.
• Enzyme Inhibition Studies: Investigated for its potential inhibitory activity against specific enzymes like histone deacetylases (HDACs), relevant to epigenetic research.
• Cell Biology: Employed in cellular assays to study effects on cell proliferation, apoptosis, and differentiation.
• Academic Research: Utilized in university and institutional laboratories for fundamental research into natural product biosynthesis and bioactivity.

Basic Information

Product Name	Nazumamide A
CAS No.	138949-86-7
Molecular Formula	C31H49N5O7
Molecular Weight	603.76 g/mol
Synonyms	Nazumamide; Nazumamide A; Largamide A; Cyclo[(2S,3R)-3-hydroxy-2-methylpentanoyl-L-valyl-N-methyl-L-phenylalanyl-L-leucyl-(3S,4E)-3-hydroxy-7-methyl-4-octenoyl-L-alanyl-(3S,6S)-3-amino-6-hydroxy-2-oxo-1-piperidineacetyl]; L-Valine, N-[N-[N-[N2-[(2S,3R)-3-hydroxy-2-methyl-1-oxopentyl]-L-valyl]-N-methyl-L-phenylalanyl]-L-leucyl]-(3S,4E)-3-hydroxy-7-methyl-4-octenoyl-L-alanyl]-(3S,6S)-3-amino-6-hydroxy-2-oxo-1-piperidineacetate (1:1)
EINECS	Contact for details

Quality Control

Every batch of Nazumamide A is produced and analyzed under strict quality management protocols to ensure identity, purity, and consistency for research applications. We provide comprehensive analytical documentation, including HPLC chromatograms and MS data, to support your work. A detailed Certificate of Analysis (COA) is available for each lot, confirming compliance with our stringent in-house specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC-MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0 %
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.