Description

Neuropeptide Y, Pro(34)- is a synthetic peptide analog of the endogenous neurotransmitter Neuropeptide Y (NPY), specifically modified at position 34. This compound is a crucial research tool for studying the complex NPY receptor system, particularly the Y1 receptor subtype, due to its altered binding affinity and selectivity. It is essential for researchers and developers in pharmaceutical R&D, neuroscience, and metabolic disorder studies who require high-purity, well-characterized peptides for receptor binding assays, signal transduction research, and the development of novel therapeutic agents.

Application

• Neuroscience Research: Used as a selective ligand in receptor binding studies to investigate the role of NPY and its receptors in the central and peripheral nervous systems.
• Pharmacological Profiling: Critical for characterizing the selectivity and affinity of new drug candidates targeting NPY Y1 receptors.
• Metabolic Disorder Studies: Applied in research models exploring NPY's involvement in appetite regulation, energy homeostasis, and obesity.
• Cardiovascular Research: Utilized to study the effects of NPY on vascular tone, heart rate, and blood pressure regulation.
• Biochemical Assay Development: Serves as a reference standard in the development and validation of immunoassays (ELISA, RIA) and functional cellular assays.
• Academic & Institutional Research: A key reagent for basic science investigations into neuropeptide signaling pathways and their physiological implications.

Basic Information

Product Name	Neuropeptide Y, Pro(34)-
CAS No.	138874-38-1
Molecular Formula	C190H287N55O57S
Molecular Weight	4252.7 g/mol
Synonyms	[Pro34]-Neuropeptide Y; NPY, Pro(34)-; Human, Rat Neuropeptide Y (Pro34); [Pro34]NPY; Neuropeptide Y (Pro34); NPY (Pro34); Pro34-Neuropeptide Y; [Pro34]-NPY
EINECS	Contact for details

Quality Control

Every batch of Neuropeptide Y, Pro(34)- is manufactured and analyzed under strict quality protocols to ensure identity, purity, and consistency. Our products undergo rigorous quality testing, including HPLC, MS, and amino acid analysis, to ensure compliance with high-purity research-grade standards. Certificates of Analysis (COA) detailing purity, peptide content, and analytical data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store desiccated at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Amino Acid Analysis	Conforms to theoretical composition
Solubility	Soluble in water or dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.