Description

tert-Butyloxycarbonyl-Valyl-Benzylseryl-Glutaminyl-Asparaginyl-(Brz)Tyrosine is a protected pentapeptide sequence, a crucial building block in advanced peptide synthesis and pharmaceutical research. This compound is valued for its role in constructing complex bioactive peptides, where the tert-butyloxycarbonyl (Boc) and benzyl (Bzl) protecting groups provide orthogonal deprotection strategies. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on developing novel therapeutic agents, diagnostic tools, and biochemical probes.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic fragment in the production of complex peptide-based drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a standard or substrate in enzymatic studies, receptor-ligand binding assays, and metabolic pathway investigations.
• Peptide Library Synthesis: A critical component in solid-phase and solution-phase peptide synthesis for creating diverse libraries for drug discovery screening.
• Proteomics & Diagnostics: Employed in the development of specific peptide antigens, antibodies, and diagnostic assay components.
• Academic Research: Utilized in university and institutional labs for studying peptide chemistry, protecting group strategies, and structure-activity relationships (SAR).
• Custom Peptide Manufacturing: A starting material for contract research and manufacturing organizations (CRMOs) producing bespoke peptides for clients.

Basic Information

Product Name	tert-Butyloxycarbonyl-Valyl-Benzylseryl-Glutaminyl-Asparaginyl-(Brz)Tyrosine
CAS No.	138865-76-6
Molecular Formula	C43H60N8O14
Molecular Weight	912.99 g/mol
Synonyms	Boc-Val-Ser(Bzl)-Gln-Asn-Tyr(BrZ); Boc-Val-Ser(Bzl)-Gln-Asn-Tyr(Br-Z); Pentapeptide Boc-Val-Ser(Bzl)-Gln-Asn-Tyr(BrZ); N-[(1,1-Dimethylethoxy)carbonyl]-L-valyl-N5-(benzyloxycarbonyl)-O-benzyl-L-seryl-L-α-glutaminyl-L-α-asparaginyl-3-bromo-N-[(benzyloxy)carbonyl]-L-tyrosine; Boc-Val-Ser(Bzl)-Gln-Asn-Tyr(Br-Z) OH; 138865-76-6; Boc-Val-Ser(Bzl)-Gln-Asn-Tyr(BrZ)-OH
EINECS	Contact for details

Quality Control

Our tert-Butyloxycarbonyl-Valyl-Benzylseryl-Glutaminyl-Asparaginyl-(Brz)Tyrosine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, MS for identity confirmation, and chiral analysis, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Conforms to ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.