Description

Trypomastigote Specific Surface Antigen is a highly purified, biologically active glycoprotein antigen derived from the surface of the trypomastigote stage of Trypanosoma cruzi. This compound is critical for research and diagnostic applications targeting Chagas disease, providing a specific marker for parasite detection and immunological studies. It is essential for pharmaceutical R&D laboratories, diagnostic kit manufacturers, and academic institutions focused on tropical medicine and parasitology.

Application

• Diagnostic Assay Development: As a key antigenic component in ELISA, Western Blot, and rapid test kits for the serological diagnosis of Chagas disease.
• Vaccine Research: Used as a target antigen in the research and development of potential vaccines against Trypanosoma cruzi infection.
• Immunological Studies: Employed to study host-parasite interactions, immune evasion mechanisms, and the specific antibody response in infected hosts.
• Quality Control Reference Standard: Serves as a reference material for the calibration and validation of diagnostic tests and reagent batches.
• Basic Parasitology Research: Utilized in fundamental research to understand the biology, lifecycle, and surface protein expression of the trypomastigote form.

Basic Information

Product Name	Trypomastigote Specific Surface Antigen
CAS No.	138820-03-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	TSSA; Trypomastigote Surface Antigen; Trypanosoma cruzi Trypomastigote Antigen; T. cruzi Glycoprotein Antigen; Chagas Disease Antigen; TcTSSA; Metacyclic Trypomastigote Antigen
EINECS	Contact for details

Quality Control

Our Trypomastigote Specific Surface Antigen is produced under stringent conditions to ensure batch-to-batch consistency and high biological activity. Each lot undergoes rigorous quality testing, including purity assessment, identity confirmation, and functional activity validation. Certificates of Analysis (COA) detailing specifications and test results are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, aliquot to avoid repeated freeze-thaw cycles and store under recommended conditions.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (Immunoassay)	Positive reaction with reference antisera
Purity (SDS-PAGE)	≥ 90%
Protein Content (Bradford)	≥ 1.0 mg/vial
Endotoxin Level (LAL)	< 1.0 EU/mg
Biological Activity (ELISA)	Reactivity confirmed vs. control sera
Solubility	Soluble in PBS or appropriate aqueous buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.