Description

1-Cyclopropyl-6-Fluoro-7-((1R,4R)-5-Methyl-2,5-Diaza-Bicyclo[2.2.1]Hept-2-Yl)-4-Oxo-1,4-Dihydro-Quinoline-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate of significant importance in modern medicinal chemistry. This compound is a key chiral building block in the synthesis of novel antibacterial agents, particularly fluoroquinolone derivatives. It is essential for research institutions and pharmaceutical manufacturers engaged in the development of next-generation antibiotics targeting resistant bacterial strains.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of novel fluoroquinolone antibiotics.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the chemical synthesis of complex antibacterial drug candidates.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize antibacterial potency and safety profiles.
• Process Chemistry Development: Employed in scaling up and optimizing synthetic routes for potential commercial drug production.
• Reference Standard: Used as a high-purity analytical standard for quality control and regulatory submissions in pharmaceutical manufacturing.

Basic Information

Item	Details
Product Name	1-Cyclopropyl-6-Fluoro-7-((1R,4R)-5-Methyl-2,5-Diaza-Bicyclo[2.2.1]Hept-2-Yl)-4-Oxo-1,4-Dihydro-Quinoline-3-Carboxylic Acid
CAS No.	138808-76-1
Molecular Formula	C20H21FN4O3
Molecular Weight	384.41 g/mol
Synonyms	(1R,4R)-5-Methyl-2,5-diazabicyclo[2.2.1]hept-2-yl Derivative of Ciprofloxacin; 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(5-methyl-2,5-diazabicyclo[2.2.1]hept-2-yl)-3-quinolinecarboxylic acid; (1R,4R)-5-Methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl Ciprofloxacin Analog; Ciprofloxacin Bicyclic Diamine Derivative; Advanced Fluoroquinolone Intermediate; Chiral Quinolone Carboxylic Acid
EINECS	Contact for details

Quality Control

Our 1-Cyclopropyl-6-Fluoro-7-((1R,4R)-5-Methyl-2,5-Diaza-Bicyclo[2.2.1]Hept-2-Yl)-4-Oxo-1,4-Dihydro-Quinoline-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The container should be kept in a well-ventilated area and protected from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.