Description

Fellutamide A CAS NO 138682-08-3 is a potent, naturally occurring proteasome inhibitor derived from fungal sources. This compound is of significant interest in biochemical and pharmacological research due to its specific mechanism of action, which targets the 20S proteasome core particle. It serves as a critical research tool for scientists in the fields of oncology, neurobiology, and cell signaling, enabling the study of protein degradation pathways and their role in disease progression.

Application

• Biochemical Research: Used as a specific inhibitor to study the function and regulation of the 20S proteasome in cellular processes.
• Oncology Research: Investigated for its potential anti-cancer properties by inducing apoptosis in various cancer cell lines through proteasome inhibition.
• Neurodegenerative Disease Studies: Applied in research models to understand the role of proteasomal dysfunction in diseases like Alzheimer's and Parkinson's.
• Cell Signaling Pathway Analysis: A key tool for dissecting ubiquitin-proteasome system-dependent signaling pathways.
• Pharmacology & Drug Discovery: Serves as a lead compound or reference standard in the development of novel proteasome-targeting therapeutics.
• Academic & Institutional Research: Supplied to universities and research institutes for fundamental studies in molecular biology and biochemistry.

Basic Information

Product Name	Fellutamide A
CAS No.	138682-08-3
Molecular Formula	C₂₄H₃₈N₄O₅
Molecular Weight	462.58 g/mol
Synonyms	Fellutamide A; (-)-Fellutamide A; Proteasome Inhibitor I; 2-Amino-N-[(2S,3R)-1-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-phenylpropanamido]-3-phenylpropanamido]-4-methylpentanoyl]-3-hydroxy-1-oxobutan-2-yl]hexanediamide; L-Glutamine, N2-[N-[N-[N2-(L-phenylalanyl)-L-phenylalanyl]-L-leucyl]-L-threonyl]-, (S)-; (2S)-2-Amino-4-carbamoylbutanoic acid (2S,3R)-2-[[(2S)-2-[[(2S)-2-[(2S)-2-amino-3-phenylpropanamido]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxybutyl ester
EINECS	Contact for details

Quality Control

Our Fellutamide A is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, MS). A detailed Certificate of Analysis (COA) documenting identity, purity, and assay results is provided with every shipment to support your research integrity and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, cool place. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and potency. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Solubility	Soluble in DMSO, DMF; sparingly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.