Description

Hiv Protease Substrate Iii is a specialized peptide-based compound designed for biochemical research and pharmaceutical development. This high-purity substrate is critical for the study and inhibition of HIV-1 protease, a key enzyme in the viral replication cycle. It is an essential tool for researchers in virology, enzymology, and drug discovery programs targeting antiretroviral therapies.

Application

• Enzymatic Assay Development: Primary substrate for kinetic studies and inhibition profiling of HIV-1 protease.
• High-Throughput Screening (HTS): Used in drug discovery platforms to identify and characterize novel protease inhibitors.
• Biochemical Research: Fundamental tool for investigating enzyme mechanism, substrate specificity, and cleavage efficiency.
• Diagnostic Kit Component: May be utilized in the development of in vitro diagnostic assays for antiviral resistance testing.
• Academic & Pharmaceutical R&D: Supports basic virology research and preclinical development of antiretroviral candidates.
• Quality Control: Serves as a reference standard for validating assay performance in pharmaceutical quality control labs.

Basic Information

Product Name	Hiv Protease Substrate Iii
CAS No.	138608-20-5
Molecular Formula	C45H69N11O9
Molecular Weight	908.1 g/mol
Synonyms	HIV-1 Protease Substrate III; Acetyl-Thr-Ile-Nle-r-Nle-Gln-Arg-NH2; Ac-T-Ile-Nle-ψ-(CH2-NH)-Nle-Gln-Arg-NH2; HIV Protease Substrate 3; HIV PR Substrate III; Ac-Thr-Ile-Nle-ψ-[CH2NH]-Nle-Gln-Arg-NH2; Reduced Peptide Inhibitor Substrate; HIV-1 Protease Fluorogenic Substrate III
EINECS	Contact for details

Quality Control

Our Hiv Protease Substrate Iii is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency, essential for reliable research data. Each lot undergoes comprehensive analytical testing, including HPLC for purity and MS for identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 70.0%
Solubility	Soluble in DMSO, DMF; slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.